Top 10 Best Nasal Sprays for Allergies | Buoy (2024)

Nasal sprays are an effective solution for alleviating allergy symptoms by reducing swelling and clearing mucus directly in the nasal passages where irritation from allergens often occurs. Some of them work within 15 minutes after use. Their localized treatment minimizes side effects compared to oral medications and provides fast, effective relief at the source of the problem.

This article will discuss the 10 best nasal sprays to help relieve allergy symptoms. We’ll also discuss what makes each suitable and how they can help you feel better.

Types of Nasal Sprays for Allergies

Nasal sprays are liquid medications squirted into the nasal passages to alleviate nasal congestion commonly caused by colds or allergies. They work by relieving stuffiness and reducing nasal discharge. These sprays deliver the medication in a fine mist, released from a pressurized container with a valve for adequate symptom relief.

​​There are a variety of nasal sprays on the market with different mechanisms of action. Knowing the differences is essential in making an informed choice on allergy relief. Here are the different types of nasal sprays that combat allergy symptoms.

1. Antihistamine Sprays

These sprays target nasal allergy symptoms by blocking histamine. Common side effects of antihistamine nasal sprays include the following:

  • Bitter taste
  • Dizziness
  • Drowsiness
  • Dry mouth and nose

You can get these with a prescription; some are also available over the counter. Prescription options include the following medications:

  • Patanase (Olopatadine)
  • Astelin (Azelastine)

An example of an OTC antihistamine is Astepro (the OTC version of Astelin)

2. Steroid Nasal Sprays

These are preferred for various allergy symptoms, especially for reducing inflammation and congestion. They work best when used regularly, typically once daily for a few weeks.

Common side effects of using steroid nasal sprays include the following:

  • Headaches
  • Nosebleeds
  • Nasal irritation
  • Cough

If you've had nose surgery, an untreated sinus infection, tuberculosis, or if you're pregnant or breastfeeding, talk to a doctor before using steroid nasal sprays.

Examples of steroid nasal sprays in the market are:

  • Rhinocort (Budesonide)
  • Flonase (Fluticasone)
  • Nasonex (Mometasone)
  • Nasacort (Triamcinolone)
  • Veramyst (Fluticasone furoate)

3. Mast Cell Inhibitor Sprays

Mast cell inhibitor nasal sprays work by helping prevent the release of histamine, reducing allergy symptoms when used consistently. They help control allergic reactions over time but don't provide quick relief. Still, they're essential for long-term allergy management.

Typical side effects are the following:

  • Sneezing
  • Nasal burning or irritation
  • Unpleasant taste

Given their safety profile, mast cell inhibitor sprays suit many users, including children and adults.

An example of a mast cell inhibitor nasal spray available OTC is Cromolyn sodium (Nasalcrom).

4. Decongestant Sprays

Decongestant nasal sprays provide immediate relief for nasal congestion but should be used short-term to avoid rebound congestion. It is generally advisable to avoid use beyond 3-4 consecutive days before taking a break from use.

These sprays shrink blood vessels in the nose to lessen congestion, but they don't stop sneezing or a runny nose. They give quick relief and are often used for sudden nasal blockage.

Common side effects associated with decongestant sprays are the following:

  • Sneezing
  • Nausea
  • Sinus pains
  • Vomiting
  • Dryness or burning in the nose
  • Rebound congestion with prolonged use, which can be difficult to treat

Contraindications for decongestant sprays include individuals who have the following conditions:

  • Cardiovascular conditions, such as high blood pressure or heart disease
  • Overactive thyroid or enlarged prostate
  • Pregnant women should consult a doctor before use

Some of the decongestant nasal sprays found on the market are the following:

  • Afrin (Oxymetazoline)
  • Zicam (Oxymetazoline)
  • Sinex (Oxymetazoline)
  • Dristan (Phenylephrine)
  • Neo-Synephrine (Phenylephrine)

5. Saline Sprays

Saline nasal sprays moisturize the nasal passages, which helps to thin mucus and moisturize the nasal lining. They can be used without side effects except for possible mild irritation.

Common side effects are minimal but can include the following:

  • Mild nasal irritation
  • A brief stinging sensation if the nasal passages are very dry

Examples of saline nasal spray products include the following:

  • Arm & Hammer Simply Saline (Sodium chloride, sodium bicarbonate)
  • Ayr (Sodium chloride 0.65%)
  • Amazon Basic Care Premium Saline Nasal Moisturizing Spray
  • Ocean nasal

6. Anticholinergic Sprays

Anticholinergic nasal sprays help dry up a runny nose by blocking acetylcholine, making them effective for allergic and nonallergic rhinitis.

Side effects associated with anticholinergic sprays can include the following:

  • Dryness of the nasal mucosa
  • Irritation or burning sensation in the nose
  • Headache
  • Dry mouth

People with narrow-angle glaucoma or trouble urinating should be careful with anticholinergics, and they're recommended for children.

The market offers Atrovent (Ipratropium bromide, 0.03%) as a prescription anticholinergic nasal spray. There are no OTC anticholinergic nasal sprays available.

Top 10 Best Nasal Sprays for Allergies

We understand the importance of effective allergy relief, especially in wanting to feel comfortable doing daily tasks without allergy symptoms. That's why we have meticulously researched and compiled a list of the top 10 best nasal sprays for allergies.

Our selection is based on carefully evaluating factors such as the following:

  • Efficacy
  • Active Ingredient
  • Potency
  • Each of administration
  • Potential side effects

Whether you're seeking immediate relief from acute symptoms or a long-term solution for managing your allergies, our top recommendations are detailed below.

Top 10 Best Nasal Sprays for Allergies | Buoy (2024)

FAQs

Which nasal allergy spray is most effective? ›

Experts say that over-the-counter (OTC) anti-inflammatory nasal sprays—such as FLONASE nasal sprays or Nasacort® 24 Hour—are the most effective form of nasal allergy symptom relief.

What is the best medicine for severe allergies? ›

Nasal steroids are often the first treatment doctors recommend. Some steroid sprays require a doctor's prescription, but three of them, budesonide (Rhinocort Allergy), fluticasone (Flonase), and triamcinolone (Nasacort Allergy 24HR), do not.

What is the best nasal spray Consumer Reports? ›

Antihistamine nasal sprays: If you've been faithfully using a nasal steroid for a couple of weeks and you're still uncomfortable, the guidelines recommend adding in a daily prescription nasal antihistamine spray, such as azelastine (Astelin, Astepro, and generic) or olopatadine (Patanase and generic).

What nasal spray can you use everyday? ›

Nasal steroids sprays (Flonase®, Nasocort®, Nasonex®, etc. ) are safe to use on a daily basis and are now largely over-the-counter. These sprays are non-addictive and typically do not cause any long term changes to the nasal passages.

Is there anything better than Flonase? ›

Official answer. Nasacort and Flonase are equally effective, safe, and well tolerated for the treatment of allergic rhinitis. Therefore the choice of either Nasacort or Flonase comes down to personal preference, availability or price.

What nasal spray has the least side effects? ›

Of the different types of allergy nasal sprays, saline nasal spray is known to cause the fewest side effects because it does not contain any medication.

What is the best long-term treatment for allergies? ›

Immunotherapy is particularly effective for allergies caused by insect stings, pollen, mold, and pet dander. Targets the root cause by modifying the immune response. Provides long-lasting relief even after treatment completion.

What is the safest antihistamine for long-term use? ›

Non-drowsy options like loratadine and cetirizine are among the safest choices for long-term allergy relief. Both medications work by blocking the effects of histamine, and people generally tolerate them well.

What is the strongest antihistamine over the counter? ›

Among second-generation antihistamines, Zyrtec is the strongest and most effective, says Dr. Staiger. The first-generation antihistamine Benadryl is also highly effective, but drowsiness is a limiting factor (unless you are looking to utilize it as a sleep aid), he says.

Which brand of nasal spray is best? ›

OTC steroid and antihistamine nasal sprays work best for treating allergy symptoms. Common examples include Flonase Allergy Relief (fluticasone), Nasacort Allergy 24 Hour (triamcinolone), and Astepro Allergy (azelastine). They're safe for both adults and children to use every day.

What is the best nasal spray for chronic sinus? ›

Nasal corticosteroids.

These nasal sprays help prevent and treat swelling. Some are available without a prescription. Examples include fluticasone (Flonase Allergy Relief, Xhance), budesonide (Rhinocort Allergy), mometasone (Nasonex 24HR Allergy) and beclomethasone (Beconase AQ, Qnasl, others).

Is there a healthy nasal spray? ›

Saline nasal spray is a safe treatment and most people don't have side effects.

Which nasal spray is best for allergies? ›

Steroid nasal sprays are like the MVPs of allergy relief—and Flonase is the best of the best. It's 24-hour relief, non-drowsy, and addresses multiple allergic symptoms, including nasal congestion, sneezing, and itchy, watery eyes while being gentle enough on your nose for daily use.

Which medicine is best for allergic rhinitis? ›

Nasal sprays — Azelastine (brand names: Astelin, Astepro) and olopatadine (brand name: Patanase) are nasal antihistamine sprays that can be used daily or when needed to relieve symptoms of postnasal drip, congestion, and sneezing. These sprays start to work within minutes after use.

What is the best nasal spray for blocked sinuses? ›

For nasal congestion, we recommend Otrivine Sinusitis Relief Nasal Spray. The spray delivers an exact medicated dose of xylometazoline hydrochloride inside the nostril to relieve the nasal congestion as well as helping to ease the sinusitis pain and pressure that you may be feeling.

Which is the best nasal spray for a blocked nose? ›

For nasal congestion, we recommend Otrivine Sinusitis Relief Nasal Spray. The spray delivers an exact medicated dose of xylometazoline hydrochloride inside the nostril to relieve the nasal congestion as well as helping to ease the sinusitis pain and pressure that you may be feeling.

Which is more effective, Flonase or Zyrtec? ›

FLONASE, a nasal spray, tends to be more effective for nasal symptoms like congestion, while Zyrtec, an oral antihistamine, may be better for symptoms like itching and hives. Individual responses vary, so personal trial is beneficial. What Should You Know About Allergies?

Which is better, Afrin or Flonase? ›

Is Afrin or Flonase better? Afrin provides a faster response to congestion with an onset of action within 10 minutes. It is not recommended for use longer than three days, however. Flonase is slower to relieve congestion symptoms but can be used safely long term.

Which is better, Flonase or Nasonex? ›

Official answer. The difference is Flonase is available over-the-counter (OTC) and Nasonex is prescription only. There is no difference in their effect or side effects. Flonase and Nasonex are both corticosteroid nasal sprays that are effective at treating hay fever, perennial allergic rhinitis and allergies.

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